Exploring Ethical Frontiers: A Content Analysis of Perceptions Surrounding Genetic Editing in Mental Health Treatments Over Time

Genetic editing has become a pivotal biotechnology tool in healthcare, enabling precise manipulation of DNA through insertions, deletions, modifications, or replacements. Its applications have expanded from treating monogenic diseases to addressing polygenic conditions, including potential mental health therapies. This study examines public sentiment and ethical considerations surrounding genetic editing systems like CRISPR- Cas9, zinc-finger nucleases (ZFNs), and transcription activator-like effector nucleases (TALENs). Analyzing a decade of medical literature, the research highlights a growing public acceptance of these technologies despite ethical concerns, such as off-target effects and unintended consequences. Positive sentiment trends indicate that social acceptance may support the integration of genetic editing in mental health treatments, driving advancements in healthcare. Addressing risks, including long-term impacts and ethical dilemmas, remains critical for responsible implementation. As public attitudes continue to improve, genetic editing may become a widely accepted therapeutic approach, fostering innovation in healthcare. Future research should focus on mitigating risks and enhancing the safety and efficacy of genetic editing to ensure its sustainable development and adoption.